导师层次：硕士研究生导师（基础医学院）
研究方向：分子神经生物学
擅长领域：生物大分子结构与相互作用
电子邮箱：yangxy1900@zzu.edu.cn
个人简历：
2013-07 至 2017-06, 华中科技大学, 生物物理, 博士 ；
2017-07 至 2019-11, 华中科技大学，生物医学工程流动站 ，博士后；
2019-11 至今, 郑州大学, 第二附属医院, 助理研究员 。
科研学术成果：
一、科研项目:
（1）中国博士后科学基金会第62批面上资助一项；
（2）国家自然科学基金委员会面上项目一项。
二、代表性论著：
(1) Yang Xiaoyu ; Zhou Jie; Sun Lei; Wei Zhiyi; Gao Jianying; Gong Weimin; Xu Rui Ming; Rao Zi he; Liu Yingfang ; Structural basis for the function of DCN-1 in protein neddylation, Journal of Biological Chemistry, 2007, 282(34): 24490-24494.
(2) Yang Xiaoyu ; Wang Shen; Sheng Yi; Zhang Mingshu; Zou Wenjuan; Wu Lijie; Kang Lijun; Rizo Josep; Zhang Rongguang; Xu Tao; Ma Cong ; Syntaxin opening by the MUN domain underlies the functi on of Munc13 in synaptic-vesicle priming, Nature Structural & Molecular Biology, 2015, 22(7): 547 -554.
(3) Wang Shen; Choi Ucheor B; Gong Jihong; Yang Xiaoyu ; Li Yun; Wang Austin L; Yang Xiaofei; Brunger Axel T; Ma Cong ; Conformational change of syntaxin linker region induced by Munc13s init iates SNARE complex formation in synaptic exocytosis, The EMBO Journal, 2017, 36(6): 816-829.
(4) Wenjie Huang, Zhe Liu, Fan Yang, Huan Zhou, Xin Yong, Xiaoyu Yang, Yifei Zhou, Lijia Xue, Yihong Zhang, Dingdong Liu, Wentong Meng, Wenming Zhang, Xiaohu Zhang, Xiaofei Shen,Qingxiang Sun, Li Li, Cong Ma,Yuquan Wei,Daniel D. Billadeau, Xianming Mo, and Da Jia.Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCH. PNAS， 2019, 116(45): 22598-22608.
(5) Wang Xianping; Gong Jihong; Zhu Le; Wang Shen; Yang Xiaoyu; Xu Yuanyuan; Yang Xiaofei; Ma Cong ; Munc13 activates the Munc18-1/syntaxin-1 complex and enables Munc18-1 to prime SNARE assem bly, The EMBO Journal, 2020, 39(16): e103631.
(6) Xiaoyu Yang ; Jing Li; Liting Zhao; Yazhuo Chen; Zhijun Cui; Taotao Xu; Xu Li; Shufang Wu; Yan Zhang ; Targeting adipocytic discoidin domain receptor 2 impedes fat gain while increasing bo ne mass, cell death & differentiation, 2021.
(7) Yanrui Yang,Jiang Chen,Xue Chen,Di Li,Jianfeng He,Shen Wang,Shun Zhao,Xiaoyu Yang,Shikun Deng,Chunfang Tong,Dou Wang,Zhenzhen Guo,Dong Li,Cong Ma,Xin Liang,Yun S Shi,Jia-Jia Liu.Endophilin A1 drives acute structural plasticity of dendritic spines in response to Ca2+/calmodulin. J Cell Biol.2021 Jun 7;220(6):e202007172.
